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\u53f0\u7063\u65b0\u51a0\u75c5\u6bd2\u75ab\u60c5\u4ecd\u672a\u5e73\u606f\uff0c\u8a31\u591a\u95dc\u5fc3\u75ab\u60c5\u7684\u6c11\u773e\u53ef\u80fd\u66fe\u7d93\u807d\u8aaa\u904e\uff0c\u82e5\u6709\u7cd6\u5c3f\u75c5\u7b49\u6162\u6027\u75c5\uff0c\u53ef\u80fd\u6703\u63d0\u9ad8\u65b0\u51a0\u75c5\u6bd2\u80ba\u708e\u7684\u91cd\u75c7\u3001\u6b7b\u4ea1\u98a8\u96aa\u3002\u800c\u6162\u6027\u75c5\u60a3\u8005\u4e5f\u56e0\u6b64\u88ab\u8af8\u591a\u570b\u5bb6\u5217\u5165\u512a\u5148\u65bd\u6253\u5c0d\u8c61\u4e4b\u4e00\u3002<\/p>\n

\n

\u9019\u4e0d\u7981\u4ee4\u7cd6\u53cb\u5011\u958b\u59cb\u64d4\u5fc3\uff0c\u81ea\u5df1\u7684\u8655\u5883\u662f\u4e0d\u662f\u76f8\u7576\u5371\u96aa\u5462\uff1f\u5176\u5be6\uff0c\u5c0d\u75ab\u60c5\u4fdd\u6301\u8b66\u60d5\u662f\u597d\u4e8b\uff0c\u4f46\u4e5f\u4e0d\u7528\u592a\u904e\u64d4\u5fc3\u800c\u5f92\u589e\u5fc3\u7406\u58d3\u529b\uff0c\u56e0\u70ba\u8fd1\u671f\u7684\u4e00\u9805\u5fb7\u570b\u7814\u7a76\u767c\u73fe\uff0c\u7cd6\u5c3f\u75c5\u60a3\u8005\u53ea\u8981\u597d\u597d\u63a7\u5236\u8840\u7cd6\uff0c\u91cd\u75c7\u5316\u7684\u98a8\u96aa\u4e26\u4e0d\u6703\u6bd4\u4e00\u822c\u4eba\u70ba\u9ad8\u3002<\/p>\n

\n

\u5fb7\u570b\u7cd6\u5c3f\u75c5\u7814\u7a76\u4e2d\u5fc3\u8207\u5fb7\u570b\u675c\u585e\u9053\u592b\u6d77\u56e0\u91cc\u5e0c\u00b7\u6d77\u6d85\u5927\u5b78\uff08Heinrich-Heine-Universit\u00e4t D\u00fcsseldorf\uff09\u5408\u4f5c\u7684\u4e00\u9805\u7814\u7a76\u767c\u73fe\uff0c\u7cd6\u5c3f\u75c5\u60a3\u8005\u82e5\u662f\u8840\u7cd6\u63a7\u5236\u5f97\u5b9c\uff0c\u4e26\u4e0d\u6703\u8b93\u65b0\u51a0\u80ba\u708e\u7684\u91cd\u75c7\u98a8\u96aa\u4e0a\u5347\uff1b\u53cd\u4e4b\uff0c\u82e5\u662f\u672a\u80fd\u597d\u597d\u63a7\u5236\u8840\u7cd6\uff0c\u53ef\u80fd\u6703\u8b93\u6b7b\u4ea1\u7387\u5927\u589e\u5230\u5c07\u8fd19\u500d\u4e4b\u591a\u3002<\/p>\n

\n

\u7cd6\u5c3f\u75c5\u60a3\u8005\u8840\u7cd6\u82e5\u80fd\u78ba\u5be6\u63a7\u5236\uff0c\u65b0\u51a0\u75c5\u6bd2\u80ba\u708e\u91cd\u75c7\u5316\u98a8\u96aa\u548c\u4e00\u822c\u4eba\u4e26\u7121\u986f\u8457\u5dee\u7570<\/span>
\n<\/b><\/p>\n

\u6b64\u6b21\u7814\u7a76\u70ba\u6d41\u884c\u75c5\u5b78\u535a\u58ebSabrina Schlesinger\u7b49\u4eba\u6240\u9032\u884c\uff0c\u767c\u8868\u65bc2021\u5e744\u670828\u65e5\u3002\u7814\u7a76\u91dd\u5c0d22\u9805\u7814\u7a76\u4e2d\u76841,7687\u540d\u7cd6\u5c3f\u75c5\u60a3\u8005\u8cc7\u6599\u9032\u884c\u5206\u6790\uff0c\u7814\u7a76\u6210\u679c\u4e5f\u767c\u8868\u65bc\u6b50\u6d32\u7cd6\u5c3f\u75c5\u5b78\u6703\uff08EASD\uff09\u51fa\u7248\u4e4b\u91ab\u5b78\u671f\u520a\u300a\u7cd6\u5c3f\u75c5\u5b78\uff08Diabetologia\uff09\u300b\u4e4b\u4e2d\u3002<\/p>\n

\n

\u5728\u904e\u53bb\uff0c\u7cd6\u5c3f\u75c5\u5c31\u88ab\u8a8d\u70ba\u662f\u65b0\u51a0\u80ba\u708e\u7684\u5371\u96aa\u56e0\u5b50\uff0c\u548c\u7cd6\u5c3f\u75c5\u53ca\u65b0\u51a0\u75c5\u6bd2\u4e4b\u9593\u95dc\u4fc2\u6709\u95dc\u7684\u7814\u7a76\u4e2d\u767c\u73fe\uff0c\u7cd6\u5c3f\u75c5\u60a3\u8005\u6bd4\u8d77\u6c92\u6709\u7cd6\u5c3f\u75c5\u7684\u65cf\u7fa4\uff0c\u611f\u67d3\u65b0\u51a0\u75c5\u6bd2\u5f8c\u6b7b\u4ea1\u98a8\u96aa\u5927\u7d04\u6703\u63d0\u9ad82\uff5e3\u500d\u4e4b\u591a\u3002\u4e0d\u904e\uff0c\u53ea\u6709\u7576\u7cd6\u5c3f\u75c5\u60a3\u8005\u7684\u8840\u7cd6\u672a\u7372\u5f97\u826f\u597d\u7684\u63a7\u5236\uff0c\u98a8\u96aa\u624d\u6703\u8f03\u9ad8\uff0c\u82e5\u80fd\u7372\u5f97\u826f\u597d\u63a7\u5236\uff0c\u5247\u548c\u4e00\u822c\u4eba\u7684\u91cd\u75c7\u5316\u98a8\u96aa\u4e26\u7121\u986f\u8457\u5dee\u7570\u3002<\/p>\n

\n

\u7f8e\u570b\u7cd6\u5c3f\u75c5\u5b78\u6703\uff08ADA\uff09\u4e5f\u66fe\u6307\u51fa\uff0c\u7cd6\u5c3f\u75c5\u7372\u5f97\u826f\u597d\u7684\u63a7\u5236\uff0c\u6709\u5229\u65bc\u6291\u5236\u65b0\u51a0\u75c5\u6bd2\u91cd\u75c7\u5316\u7684\u98a8\u96aa\uff1b\u53cd\u4e4b\uff0c\u82e5\u672a\u80fd\u7372\u5f97\u826f\u597d\u63a7\u5236\uff0c\u5247\u75c5\u60c5\u53ef\u80fd\u6703\u8f03\u70ba\u56b4\u91cd\u3002\u800c\u4e14\u9019\u6a23\u7684\u7d50\u679c\u548c\u7cd6\u5c3f\u75c5\u7684\u985e\u578b\uff0c\u59821\u578b\u7cd6\u5c3f\u75c5\u30012\u578b\u7cd6\u5c3f\u75c5\uff0c\u4ee5\u53ca\u5e74\u9f61\u3001\u4f75\u767c\u75c7\u7b49\u56e0\u7d20\u7121\u95dc\uff0c\u53ea\u8981\u8b93\u6301\u7e8c\u63a5\u53d7\u6cbb\u7642\u3001\u63a7\u5236\u75c5\u60c5\uff0c\u5c31\u53ef\u80fd\u6e1b\u5c11\u91cd\u75c7\u98a8\u96aa\uff0c\u9019\u4e5f\u51f8\u986f\u4e86\u63a7\u5236\u75c5\u60c5\u7684\u91cd\u8981\u6027\u3002<\/p>\n

\n

\u7cd6\u5c3f\u75c5\u60a3\u8005\u8840\u7cd6\u672a\u7372\u63a7\u5236\uff0c\u6b7b\u65bc\u65b0\u51a0\u75c5\u6bd2\u80ba\u708e\u98a8\u96aa\u589e\u52a0\u52308.6\u500d<\/span><\/span><\/p>\n

<\/p>\n

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\n<\/span><\/p>\n

\u6b64\u6b21\u7814\u7a76\u4e2d\u767c\u73fe\uff0c\u8840\u7cd6\u6578\u503c\u70ba108mg\uff0fdL\u3001\u7372\u5f97\u826f\u597d\u63a7\u5236\u7684\u60a3\u8005\uff0c\u91cd\u75c7\u5316\u98a8\u96aa\u4e26\u672a\u986f\u8457\u63d0\u5347\uff1b\u800c\u4f4f\u9662\u6642\u6216\u6b7b\u4ea1\u6642\u8840\u7cd6\u9ad8\u9054198mg\uff0fdL\u3001\u672a\u7372\u5f97\u826f\u597d\u63a7\u5236\u7684\u60a3\u8005\uff0c\u6b7b\u65bc\u65b0\u578b\u51a0\u72c0\u75c5\u6bd2\u7684\u98a8\u96aa\u5927\u7d04\u4e0a\u5347\u52308.6\u500d<\/span>\u3002<\/p>\n

\n

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\n

\u6709\u670d\u7528\u964d\u8840\u7cd6\u85e5\u7269\u300c\u4e8c\u7532\u96d9\u80cd\uff08Metformin\uff0c\u5e38\u898b\u5546\u54c1\u540d\uff1a\u5eab\u9b6f\u5316\u9320\uff09\u300d\u76842\u578b\u7cd6\u5c3f\u75c5\u60a3\u8005\uff0c\u6bd4\u8d77\u6c92\u6709\u670d\u7528\u7684\u60a3\u8005\uff0c\u6b7b\u65bc\u65b0\u578b\u51a0\u72c0\u75c5\u6bd2\u7684\u6a5f\u7387\u4f4e\u4e8650\uff05\u3002\u4e8c\u7532\u96d9\u80cd\u5728\u8a31\u591a\u570b\u5bb6\uff08\u5305\u62ec\u53f0\u7063\uff09\u90fd\u662f\u7cd6\u5c3f\u75c5\u4e00\u7dda\u85e5\u7269\u3002<\/p>\n

\n

\u540c\u6642\uff0c\u7814\u7a76\u4e5f\u767c\u73fe\u6709\u65bd\u7528\u80f0\u5cf6\u7d20\u7684\u7cd6\u5c3f\u75c5\u60a3\u8005\uff0c\u6bd4\u8d77\u672a\u4f7f\u7528\u7684\u60a3\u8005\uff0c\u6b7b\u65bc\u65b0\u51a0\u80ba\u708e\u7684\u6a5f\u7387\u9ad8\u51fa75\uff05\uff0c\u9019\u53ef\u80fd\u662f\u56e0\u70ba2\u578b\u7cd6\u5c3f\u75c5\u60a3\u8005\u82e5\u5fc5\u9808\u4f7f\u7528\u80f0\u5cf6\u7d20\uff0c\u5f80\u5f80\u610f\u5473\u8457\u75c5\u60c5\u8f03\u70ba\u56b4\u91cd\u7684\u7de3\u6545\u3002<\/p>\n

\n

\u9664\u6b64\u4e4b\u5916\uff0c\u7cd6\u5c3f\u75c5\u60a3\u8005\u6b7b\u65bc\u65b0\u51a0\u80ba\u708e\u7684\u98a8\u96aa\u4e2d\uff0c\u7537\u6027\u60a3\u8005\u7684\u6b7b\u4ea1\u98a8\u96aa\u6bd4\u5973\u6027\u60a3\u8005\u9ad8\u51fa28\uff05\uff1b65\u6b72\u4ee5\u4e0a\u7cd6\u5c3f\u75c5\u60a3\u8005\u6b7b\u65bc\u65b0\u51a0\u80ba\u708e\u7684\u98a8\u96aa\u53c8\u662f\u672a\u6eff65\u6b72\u60a3\u8005\u76843\u500d\u4e4b\u591a\uff0c\u800c\u4e14\u5e74\u7d00\u6bcf\u4e0a\u53475\u6b72\uff0c\u53c8\u589e\u52a043\uff05\u3002<\/p>\n

\n

\u7814\u7a76\u4eba\u54e1Sabrina Schlesinger\u535a\u58eb\u4e5f\u5f37\u8abf\uff0c\u9019\u53ea\u662f\u76ee\u524d\u7684\u7814\u7a76\u7d50\u679c\uff0c\u7cd6\u5c3f\u75c5\u60a3\u8207\u65b0\u51a0\u80ba\u708e\u91cd\u75c7\u5316\u7684\u95dc\u4fc2\u4ecd\u9808\u900f\u904e\u66f4\u591a\u7814\u7a76\u4f86\u91d0\u6e05\u3002\u4e0d\u904e\uff0c\u4e5f\u5df2\u7d93\u78ba\u5be6\u89c0\u5bdf\u5230\u7cd6\u5c3f\u75c5\u60a3\u8005\u82e5\u672a\u80fd\u78ba\u5be6\u6cbb\u7642\uff0c\u6216\u662f\u7537\u6027\u3001\u9ad8\u9f61\u8005\uff0c\u91cd\u75c7\u5316\u7684\u98a8\u96aa\u90fd\u6703\u8f03\u9ad8\uff0c\u5fc5\u9808\u591a\u52a0\u6ce8\u610f\u3002\u56e0\u6b64\u5efa\u8b70\u6709\u7cd6\u5c3f\u75c5\u554f\u984c\u52d9\u5fc5\u7a4d\u6975\u6cbb\u7642\uff0c\u751a\u81f3\u53ef\u5c07\u4e4b\u8996\u70ba\u5c0d\u6297\u65b0\u51a0\u80ba\u708e\u7684\u624b\u6bb5\u4e4b\u4e00\u3002<\/p>\n

\n

\u63a7\u8840\u7cd6\u9019\u6a23\u5403\u8840\u7cd6\u4e0d\u98c6\u9ad8<\/span><\/span><\/p>\n

<\/p>\n

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\n<\/span><\/p>\n

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\n

\u8981\u6ce8\u610f\u7684\u662f\uff0c\u852c\u83dc\u6c34\u679c\u4e2d\u96d6\u7136\u4e5f\u6709\u6c34\u6eb6\u6027\u81b3\u98df\u7e96\u7dad\uff0c\u4f46\u542b\u91cf\u8f03\u4e0d\u8c50\u5bcc\uff0c\u662f\u6bd4\u8f03\u96e3\u900f\u904e\u852c\u679c\u4f86\u651d\u53d6\u5230\u7684\u3002\u800c\u5bcc\u542b\u6c34\u6eb6\u6027\u81b3\u98df\u7e96\u7dad\u7684\u98df\u6750\uff0c\u5927\u81f4\u4e0a\u6709\u6606\u5e03\u3001\u6d77\u5e36\u82bd\u7b49\u85fb\u985e\uff0c\u4ee5\u53ca\u5927\u9ea5\u3001\u71d5\u9ea5\u7247\u3001\u849f\u84bb\u7b49\u3002<\/p>\n

\n

\u5403\u5b8c\u81b3\u98df\u7e96\u7dad\u5f8c\u63a5\u8457\u53ef\u4ee5\u958b\u59cb\u5403\u8089\u985e\u7b49\u5bcc\u542b\u86cb\u767d\u8cea\u53ca\u6cb9\u8102<\/span>\u7684\u98df\u7269\uff0c\u628a\u91a3\u985e\u542b\u91cf\u9ad8\u7684\u98df\u6750\u7559\u5728\u6700\u5f8c\uff0c\u9664\u4e86\u80fd\u907f\u514d\u8840\u7cd6\u98c6\u9ad8\uff0c\u6c34\u6eb6\u6027\u81b3\u98df\u7e96\u7dad\u540c\u6642\u4e5f\u6709\u6e1b\u7de9\u81bd\u56fa\u9187\u5438\u6536\u7684\u6548\u679c\u3002<\/p>\n

\n

\u800c\u9664\u4e86\u6ce8\u610f\u98f2\u98df\u7684\u9806\u5e8f\u4ee5\u5916\uff0c\u6e1b\u6162\u7528\u9910\u901f\u5ea6\u4e5f\u5f88\u91cd\u8981\uff0c\u9084\u6709\u52d9\u5fc5\u6ce8\u610f\u4e0d\u8981\u559d\u542b\u7cd6\u98f2\u6599\uff0c\u624d\u80fd\u66f4\u597d\u5730\u63a7\u5236\u8840\u7cd6\u3002<\/span><\/p>\n

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\u64b0\u6587\u8005\uff1a\u91ab\u806f\u7db2\u7de8\u8f2f\u7fa4<\/p>\n<\/p>\n

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