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style=\"font-size: 18px\">\u7814\u7a76\u767c\u73fe\u5403\u7279\u5b9a\u7a2e\u985e\u8d77\u53f8\u80fd\u5e6b\u52a9\u63d0\u9ad8\u8a8d\u77e5\u529f\u80fd\u3001\u9810\u9632\u5931\u667a\u75c7<\/span><\/b><\/p>\n<p><b><span style=\"font-size: 18px\"><\/p>\n<p><p><\/span><br \/>\n<\/b><\/p>\n<\/p>\n<p>\u65e5\u672cNPO\u6cd5\u4eba\u8d77\u53f8\u5c08\u696d\u5354\u6703CPA\u8a8d\u8b49\u8d77\u53f8\u5c08\u5bb6\u3001\u6599\u7406\u7814\u7a76\u5bb6\u5c0f\u91ce\u5b5d\u4e88\u8868\u793a\uff0c\u5361\u8292\u8c9d\u723e\u4e7e\u916a\u662f\u4e00\u7a2e\u76f8\u7576\u7f8e\u5473\u53c8\u5065\u5eb7\u7684\u8d77\u53f8\uff0c\u5916\u5074\u6703\u9644\u8457\u4e00\u5c64\u767d\u8272\u9ef4\u83cc\u662f\u5b83\u7684\u7279\u8272\u3002<\/p>\n<p>\n<\/p>\n<p>\u9019\u7a2e\u767d\u8272\u9ef4\u83cc\u548c\u4e00\u822c\u6703\u5f15\u8d77\u98df\u7269\u4e2d\u6bd2\u7684\u6709\u5bb3\u9ef4\u83cc\u7a2e\u985e\u5b8c\u5168\u4e0d\u540c\uff0c\u6703\u5728\u719f\u6210\u7684\u904e\u7a0b\u4e4b\u4e2d\u5206\u89e3\u86cb\u767d\u8cea\u3001\u88fd\u9020\u9175\u7d20\uff0c\u8b93\u8d77\u53f8\u8b8a\u5f97\u67d4\u5ae9\u53ef\u53e3\uff0c\u540c\u6642\u8d77\u53f8\u7368\u7279\u7684\u9bae\u5473\u4e5f\u6703\u5927\u5e45\u63d0\u5347\u3002<\/p>\n<p>\n<\/p>\n<p>\u9019\u7a2e\u8d77\u53f8\u5f15\u8d77\u95dc\u6ce8\u7576\u7136\u4e0d\u662f\u53ea\u6709\u7f8e\u5473\u800c\u5df2\uff0c\u8fd1\u5e74\u7814\u7a76\u767c\u73fe\u6709\u4e9b\u98df\u6750\u80fd\u5e6b\u52a9\u9810\u9632\u5931\u667a\uff0c\u5361\u8292\u8c9d\u723e\u4e7e\u916a\u6b63\u662f\u5176\u4e2d\u4e00\u7a2e\u3002<\/p>\n<p>\n<\/p>\n<p>2015\u5e74\u6771\u4eac\u5927\u5b78\u767c\u8868\u7684\u7814\u7a76\u6307\u51fa\uff0c\u5361\u8292\u8c9d\u723e\u4e7e\u916a\u542b\u6709\u6cb9\u9178\u91af\u80fa\uff08oleamide\uff09\u3001\u812b\u6c2b\u9ea5\u89d2\u56fa\u9187\uff08dehydroergosterol\uff09\u7b49\u7269\u8cea\uff0c\u53ef\u80fd\u5177\u6709\u6291\u5236\u8166\u5167\u5931\u667a\u7269\u8cea\u300c\u6fb1\u7c89\u6a23\u86cb\u767d\u03b2\u300d\u7522\u751f\u7684\u6548\u679c\uff0c\u53ef\u671b\u5e6b\u52a9\u9810\u9632\u5931\u667a\u75c7\uff0c\u7814\u7a76\u767c\u8868\u65bc\u77e5\u540d\u91ab\u5b78\u671f\u520a\u300aPLOS ONE\u300b\u4e4b\u4e2d\u3002<\/p>\n<p>\n<\/p>\n<p>\u65e5\u672c\u5730\u65b9\u7368\u7acb\u884c\u653f\u6cd5\u4eba\u6771\u4eac\u90fd\u5065\u5eb7\u9577\u58fd\u91ab\u7642\u4e2d\u5fc3\u7814\u7a76\u6240\u91d1\u61b2\u7d93\u535a\u58eb\uff0c\u4e5f\u66fe\u91dd\u5c0d\u8d77\u53f8\u8207\u5931\u667a\u9593\u7684\u95dc\u4fc2\u9032\u884c\u904e\u7814\u7a76\uff0c\u7814\u7a76\u5c0f\u7d44\u4ee52017\u5e74\u5c45\u4f4f\u65bc\u6771\u4eac\u76841035\u540d65\u6b72\u4ee5\u4e0a\u9ad8\u9f61\u5973\u6027\u4f5c\u70ba\u5c0d\u8c61\uff0c\u8abf\u67e5\u4ed6\u5011\u7684\u98f2\u98df\u7fd2\u6163\u3001\u8d77\u53f8\u651d\u53d6\u91cf\uff0c\u4e26\u5c0d\u4ed6\u5011\u65bd\u884c\u8a8d\u77e5\u529f\u80fd\u6e2c\u8a66\uff0c\u5f97\u5230\u4ee5\u4e0b\u7d50\u679c\uff1a<\/p>\n<p>\n<\/p>\n<p>\u25cf\u6bcf\u5929\u5403\u8d77\u53f8\u7684\u4eba\u7d04\u670926\uff05\uff0c\u5b8c\u5168\u4e0d\u5403\u7684\u670919.1\uff05\u3002\n<\/p>\n<p>\u25cf\u6bcf\u5929\u5403\u8d77\u53f8\u7684\u4eba\u6bd4\u8d77\u4e0d\u5403\u7684\u4eba\uff0c\u5728\u300c\u7c21\u77ed\u5f0f\u667a\u80fd\u8a55\u4f30\uff08Mini-Mental State Examination, MMSE\uff09\u300d\u4e2d\u7684\u5f97\u5206\u986f\u8457\u8f03\u9ad8\u3002\n<\/p>\n<p>\u25cf\u6bcf\u5929\u5403\u8d77\u53f8\u7684\u4eba\u6bd4\u8d77\u6bcf2\u5929\u54031\u6b21\u4ee5\u4e0b\u7684\u4eba\uff0c\u5728MMSE\u4e2d\u7684\u5f97\u5206\u4e5f\u986f\u8457\u8f03\u9ad8\u3002<\/p>\n<p>\n<\/p>\n<p>\u540c\u6642\u7814\u7a76\u4e5f\u91dd\u5c0d\u8d77\u53f8\u7a2e\u985e\u9032\u884c\u5206\u6790\uff0c\u767c\u73fe\u5403\u5361\u8292\u8c9d\u723e\u4e7e\u916a\u7684\u65cf\u7fa4\uff0c\u6bd4\u8d77\u5403\u5176\u4ed6\u7a2e\u985e\u8d77\u53f8\u7684\u65cf\u7fa4\uff0cMMSE\u7684\u5f97\u5206\u4e5f\u986f\u8457\u8f03\u9ad8\u3002<\/p>\n<p>\n<\/p>\n<p>\u800c\u5403\u5361\u8292\u8c9d\u723e\u4e7e\u916a\u4e4b\u6240\u4ee5\u53ef\u80fd\u5c0d\u8a8d\u77e5\u529f\u80fd\u6709\u5e6b\u52a9\uff0c\u91d1\u61b2\u7d93\u535a\u58eb\u4e5f\u63a8\u6e2c\u53ef\u80fd\u548c\u5176\u4e2d\u7684\u767d\u8272\u9ef4\u83cc\u7522\u751f\u7684\u6cb9\u9178\u9170\u80fa\u3001\u812b\u6c2b\u9ea5\u89d2\u753e\u9187\u6709\u95dc\uff0c\u6cb9\u9178\u9170\u80fa\u80fd\u5e6b\u52a9\u8166\u5167\u552f\u4e00\u7684\u514d\u75ab\u7d30\u80de\u300c\u5c0f\u81a0\u8cea\u7d30\u80de\uff08microglia\uff09\u300d\u904b\u4f5c\u3001\u63d0\u9ad8\u6297\u767c\u708e\u6548\u679c\uff0c\u53ef\u80fd\u5177\u5099\u6709\u53bb\u9664\u6fb1\u7c89\u6a23\u86cb\u767d\u03b2\u7684\u4f5c\u7528\uff1b\u812b\u6c2b\u9ea5\u89d2\u753e\u9187\u4e5f\u5177\u6709\u6291\u5236\u767c\u708e\u6548\u679c\u3002<\/p>\n<p><span><\/p>\n<p><p><\/span><\/p>\n<\/p>\n<p><b><span style=\"font-size: 18px\">\u4e0d\u6562\u76f4\u63a5\u5403\u8d77\u53f8\u6c92\u95dc\u4fc2\uff0c\u52a0\u5165\u5473\u564c\u6e6f\u4e2d\u8f15\u9b06\u5403\u9084\u80fd\u63d0\u5347\u98a8\u5473<\/span><\/b><\/p>\n<p><b><span style=\"font-size: 18px\"><\/p>\n<p><p><\/span><br \/>\n<\/b><\/p>\n<\/p>\n<p>\u65e5\u672c\u7ba1\u7406\u71df\u990a\u5e2b\u4f50\u4f50\u6728\u590f\u5b50\u4e5f\u5c07\u591a\u7a2e\u6709\u76ca\u65bc\u9632\u5931\u667a\u7684\u98df\u6750\u7d50\u5408\uff0c\u88fd\u6210\u4e86\u7c21\u55ae\u7684\u5473\u564c\u6e6f\uff0c\u5e6b\u52a9\u9810\u9632\u5931\u667a\u3002<\/p>\n<p>\n<\/p>\n<p>\u5176\u4e2d\u6703\u52a0\u5165\u542b\u6709\u03b2\u80e1\u863f\u8514\u7d20\u3001\u8304\u7d05\u7d20\uff0c\u5177\u5f37\u5927\u6297\u6c27\u5316\u6548\u679c\u7684\u756a\u8304\uff0c\u9084\u6709\u540c\u6a23\u5bcc\u542b\u7dad\u751f\u7d20\u3001\u4e5f\u5177\u6709\u6297\u6c27\u5316\u6548\u679c\u7684\u8c46\u82d7\uff1b\u518d\u4f86\u5247\u662f\u5473\u564c\u767c\u9175\u6240\u7522\u751f\u7684\u6885\u7d0d\u6c40\uff0c\u4e5f\u540c\u6a23\u6709\u6297\u6c27\u5316\u3001\u9632\u6b62\u7d30\u80de\u8001\u5316\u6548\u679c\uff0c\u9019\u4e9b\u6548\u679c\u90fd\u53ef\u80fd\u5c0d\u9810\u9632\u5931\u667a\u6709\u6b63\u9762\u5e6b\u52a9\u3002<\/p>\n<p>\n<\/p>\n<p>\u9664\u6b64\u4e4b\u5916\uff0c\u9ad8\u6e6f\u4f7f\u7528\u7684\u5c0f\u9b5a\u4e7e\u542b\u6709\u7dad\u751f\u7d20B12\uff0c\u8c46\u82d7\u4e5f\u6709\u8449\u9178\uff0c\u80fd\u5e6b\u52a9\u6e1b\u5c11\u8840\u6db2\u4e2d\u7684\u540c\u534a\u80f1\u80fa\u9178\uff08Homocysteine\uff0c\u53c8\u7a31\u9ad8\u534a\u80f1\u80fa\u9178\uff09\uff0c\u800c\u900f\u904e\u6e1b\u5c11\u540c\u534a\u80f1\u80fa\u9178\uff0c\u80fd\u5e6b\u52a9\u9810\u9632\u52d5\u8108\u786c\u5316\u3002<\/p>\n<p>\n<\/p>\n<p>\u3010\u6750\u6599\uff082\u4eba\u4efd\uff09\u3011<\/p>\n<p>(1)\u5361\u8292\u8c9d\u723e\u4e7e\u916a2\u584a\uff08\u7d0430g\uff09<\/p>\n<p>(2)\u756a\u8304\u534a\u9846<\/p>\n<p>(3)\u8c46\u82d730g<\/p>\n<p>(4)\u5c0f\u9b5a\u4e7e\u9ad8\u6e6f1.5\u676f<\/p>\n<p>(5)\u6d77\u5e36\u82bd3g<\/p>\n<p>(6)\u7d05\u5473\u564c2\u5c0f\u5319<\/p>\n<\/p>\n<p>\n<p>\u3010\u505a\u6cd5\u3011<\/p>\n<p>(1)\u756a\u8304\u5207\u5bb9\u6613\u5165\u53e3\u5927\u5c0f\uff0c\u8c46\u82d7\u53bb\u9664\u6839\u90e8\u5f8c\u52074\uff5e5cm\u9577<\/p>\n<p>(2)\u934b\u4e2d\u653e\u5165\u9ad8\u6e6f\u958b\u706b\u52a0\u71b1\uff0c\u518d\u5c07\u756a\u8304\u3001\u6d77\u5e36\u82bd\u52a0\u5165\u4e00\u8d77\u716e<\/p>\n<p>(3)\u518d\u6eb6\u5165\u5473\u564c\u3001\u52a0\u5165\u8c46\u82d7\u4ee5\u53ca\u6495\u6210\u5c0f\u584a\u7684\u5361\u8292\u8c9d\u723e\u4e7e\u916a\u5373\u53ef<\/p>\n<p>\n<p>\n<p>\n<p>\u64b0\u6587\u8005\uff1a\u91ab\u806f\u7db2\u7de8\u8f2f\u7fa4<\/p>\n<p>\u5be9\u95b1\u8005\uff1a\u66fe\u5d27\u83ef\u91ab\u5e2b<\/p>\n<\/p>\n<p> <span style=\"font-size: 18px\"> \ud83d\udd3b\u91ab\u806f\u7db2\u591a\u5143\u670d\u52d9\uff0c\u7b49\u60a8\u4f86\u9ad4\u9a57\ud83d\udd3b <\/span><\/p>\n<p> <span style=\"font-size: 18px\"> \u25fe\ufe0f \u4e86\u89e3\u5065\u5eb7\u6aa2\u67e5\uff1a <a href=\"https:\/\/med-net.com\/PrecisionMedicine?utm_source=cms\" target=\"_blank\" rel=\"noopener\"> https:\/\/med-net.com\/PrecisionMedicine <\/a> <\/span><\/p>\n<p> <span style=\"font-size: 18px\"> \u25fe\ufe0f \u7dda\u4e0a\u91ab\u5e2b\u8aee\u8a62\uff1a <a href=\"https:\/\/expert.med-net.com\/index\" target=\"_blank\" rel=\"noopener\"> https:\/\/expert.med-net.com\/index <\/a> <\/span><\/p>\n<p> <span style=\"font-size: 18px\"> \u25fe\ufe0f \u77ed\u671f\u7167\u8b77\u670d\u52d9\uff1a <a href=\"https:\/\/pse.is\/47nzj5\" target=\"_blank\" rel=\"noopener\"> https:\/\/pse.is\/47nzj5 <\/a> <\/span><\/p>\n<p> <span style=\"font-size: 18px\"> \u25fe\ufe0f AI\u667a\u80fd\u91ab\u5e2b\uff1a <a href=\"https:\/\/med-net.com\/AIDoctorWeb\" target=\"_blank\" rel=\"noopener\"> https:\/\/med-net.com\/AIDoctorWeb <\/a> <\/span><\/p>\n","protected":false},"excerpt":{"rendered":"<p>\u53f0\u706365\u6b72\u4ee5\u4e0a\u9577\u8005\u7d04\u670918.16\uff05\u5177\u6709\u8f15\u5fae\u8a8d\u77e5\u969c\u7919\uff0c\u5df2\u7d93\u7f79\u60a3\u5931\u667a\u75c7\u7684\u4e5f\u67097.78\uff05\uff0c\u5e73\u5747\u6bcf12\u4eba\u5c31\u6709\u4e00\u4f4d\u5931\u667a\uff0c [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[4],"tags":[],"class_list":["post-1129","post","type-post","status-publish","format-standard","hentry","category-disease-prevention"],"blocksy_meta":[],"_links":{"self":[{"href":"https:\/\/med-net.com\/article\/wp-json\/wp\/v2\/posts\/1129","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/med-net.com\/article\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/med-net.com\/article\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/med-net.com\/article\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/med-net.com\/article\/wp-json\/wp\/v2\/comments?post=1129"}],"version-history":[{"count":0,"href":"https:\/\/med-net.com\/article\/wp-json\/wp\/v2\/posts\/1129\/revisions"}],"wp:attachment":[{"href":"https:\/\/med-net.com\/article\/wp-json\/wp\/v2\/media?parent=1129"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/med-net.com\/article\/wp-json\/wp\/v2\/categories?post=1129"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/med-net.com\/article\/wp-json\/wp\/v2\/tags?post=1129"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}