{"id":1172,"date":"2019-12-13T08:00:00","date_gmt":"2019-12-13T00:00:00","guid":{"rendered":"https:\/\/med-net.com\/article\/3%e6%ac%be%e9%99%8d%e8%a1%80%e7%b3%96%e8%97%a5%e7%89%a9%e7%96%91%e5%90%ab%e8%87%b4%e7%99%8c%e7%89%a9%ef%bc%9f%e9%86%ab%e5%b8%ab%e5%91%bc%e7%b1%b2%ef%bc%9a%e5%8b%bf%e9%9a%a8%e4%be%bf%e5%81%9c%e8%97%a5.html"},"modified":"2019-12-13T08:00:00","modified_gmt":"2019-12-13T00:00:00","slug":"3%e6%ac%be%e9%99%8d%e8%a1%80%e7%b3%96%e8%97%a5%e7%89%a9%e7%96%91%e5%90%ab%e8%87%b4%e7%99%8c%e7%89%a9%ef%bc%9f%e9%86%ab%e5%b8%ab%e5%91%bc%e7%b1%b2%ef%bc%9a%e5%8b%bf%e9%9a%a8%e4%be%bf%e5%81%9c%e8%97%a5","status":"publish","type":"post","link":"https:\/\/med-net.com\/article\/3%e6%ac%be%e9%99%8d%e8%a1%80%e7%b3%96%e8%97%a5%e7%89%a9%e7%96%91%e5%90%ab%e8%87%b4%e7%99%8c%e7%89%a9%ef%bc%9f%e9%86%ab%e5%b8%ab%e5%91%bc%e7%b1%b2%ef%bc%9a%e5%8b%bf%e9%9a%a8%e4%be%bf%e5%81%9c%e8%97%a5.html","title":{"rendered":"3\u6b3e\u964d\u8840\u7cd6\u85e5\u7269\u7591\u542b\u81f4\u764c\u7269\uff1f\u91ab\u5e2b\u547c\u7c72\uff1a\u52ff\u96a8\u4fbf\u505c\u85e5"},"content":{"rendered":"

\u98df\u85e5\u7f72\u65bc\u76e3\u8996\u570b\u969b\u85e5\u7269\u5b89\u5168\u8a0a\u606f\u6642\uff0c\u767c\u73fe\u65b0\u52a0\u5761HSA\uff08\u5065\u5eb7\u5132\u84c4\u5e33\u6236\uff09\u516c\u5e033\u9805\u542b\u4e8c\u7532\u96d9\u80cd\uff08metformin\uff09\u6210\u5206\u4e4b\u964d\u8840\u7cd6\u85e5\u54c1\uff0c\u6aa2\u51fa\u542b\u6709\u5fae\u91cf\u300cN-\u4e9e\u785d\u57fa\u4e8c\u7532\u80fa \uff08N-Nitrosodimethylamine, NDMA\uff09\u300d\u4e0d\u7d14\u7269\uff0c\u96d6\u7d93\u67e5\u8a723\u9805\u85e5\u54c1\u5747\u672a\u6838\u51c6\u4e14\u672a\u8f38\u5165\u53f0\u7063\u3002\u4f46\u70ba\u4e86\u4fdd\u969c\u6c11\u773e\u7528\u85e5\u54c1\u8cea\u53ca\u5b89\u5168\uff0c\u98df\u85e5\u7f72\u5df2\u91dd\u5c0d\u85e5\u54c1\u4e2d\u4e9e\u785d\u80fa\u985e\u4e0d\u7d14\u7269\u63a1\u53d6\u98a8\u96aa\u7ba1\u63a7\u63aa\u65bd\u3002<\/p>\n

\n

\n

NDMA\u5c0d\u4eba\u985e\u771f\u6709\u56b4\u91cd\u7684\u5f71\u97ff\u548c\u5371\u5bb3\u55ce\uff1f\u9577\u671f\u670d\u7528\u8840\u7cd6\u85e5\u7684\u6c11\u773e\u53c8\u8a72\u6ce8\u610f\u54ea\u4e9b\u4e8b\uff1f<\/b><\/span><\/p>\n

\n

\u542bNDMA\u8840\u7cd6\u85e5\u6050\u81f4\u764c…\u7cd6\u53cb\u61c9\u627e\u66ff\u4ee3\u85e5\uff1f\u7cd6\u5c3f\u75c5\u5354\u6703\u7406\u4e8b\u9577\u9ec3\u5efa\u5be7\u8868\u793a\uff0c\u4e8c\u7532\u96d9\u80cd\uff08metaformin\uff09\u662f\u7cd6\u5c3f\u75c5\u7b2c\u4e00\u7dda\u7528\u85e5\uff0c\u5728\u5168\u4e16\u754c\u61c9\u7528\u76f8\u7576\u5ee3\u6cdb\uff0c\u4e14\u5df2\u4f7f\u7528\u5f88\u9577\u6642\u9593\uff0c\u662f\u6548\u679c\u5f88\u597d\u7684\u85e5\u7269\u3002<\/p>\n<\/p>\n

\n

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\u4e0d\u904eNDMA\u5230\u5e95\u5c0d\u4eba\u9ad4\u6709\u54ea\u4e9b\u5f71\u97ff\u5462\uff1f<\/span><\/p>\n

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\n<\/span><\/p>\n<\/p>\n

\u6797\u53e3\u9577\u5e9a\u91ab\u9662\u81e8\u5e8a\u6bd2\u7269\u4e2d\u5fc3\u4e3b\u4efb\u984f\u5b97\u6d77\u89e3\u91cb\uff0c\u4e9e\u785d\u80fa\u985e\u7684\u5316\u5408\u7269\u6709\u5f88\u591a\u7a2e\uff0cNDMA\u5c6c\u65bc\u5176\u4e2d\u4e00\u7a2e\u3002\u4ed6\u8868\u793a\uff0cNDMA\u76ee\u524d\u5728\u52d5\u7269\u5be6\u9a57\u8b49\u5be6\u6703\u589e\u52a0\u764c\u75c7\u98a8\u96aa\uff0c\u4e5f\u6703\u5f71\u97ff\u5230\u809d\u81df\u529f\u80fd\uff0c\u4f46\u5728\u4eba\u9ad4\u81e8\u5e8a\u662f\u6c92\u6709\u81f4\u764c\u8b49\u64da\u3002\n<\/p>\n

\n\u300c\u6240\u4ee5\u7f8e\u570b\u74b0\u4fdd\u7f72\uff08EPA\uff09\u628aNDMA\u5217\u70ba\u662f\u7b2c2\u7d1a\u7684\u81f4\u764c\u7269\uff0c\u4e16\u754c\u885b\u751f\u7d44\u7e54\u4e0b\u9762\u7684\u570b\u969b\u764c\u75c7\u7814\u7a76\u6a5f\u69cb\uff08IARC\uff09\u4e5f\u628a\u5b83\u5217\u70ba\u662f2A\u7d1a\u7684\u81f4\u764c\u7269\uff0c\u4ee3\u8868\u52d5\u7269\u5be6\u9a57\u6709\u81f4\u764c\u6027\u6703\u589e\u52a0\u809d\u764c\u98a8\u96aa\uff0c\u4f46\u5728\u4eba\u9ad4\u4e0a\u6c92\u6709\u81f4\u764c\u8b49\u64da\u3002\u300d\u984f\u5b97\u6d77\u6307\u51fa\u3002<\/p>\n


\n<\/span><\/p>\n

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\u5c0f\u5fc3\u4f75\u767c\u75c7\uff01\u91ab\uff1a\u7cd6\u53cb\u7528\u85e5\u9700\u6ce8\u610f\u300c1\u4ef6\u4e8b\u300d
\n\uff0c<\/span>\u90a3\u9ebc\u9577\u671f\u670d\u7528\u8840\u7cd6\u85e5\u7684\u6c11\u773e\u53c8\u8a72\u6ce8\u610f\u54ea\u4e9b\u4e8b\u5462\uff1f<\/span><\/span><\/p>\n<\/p>\n

\n

\u9ec3\u5efa\u5be7\u63d0\u9192\u6709\u670d\u7528metformin\u7684\u6c11\u773e\uff0cNDMA\u96d6\u5177\u52d5\u7269\u81f4\u764c\u6027\uff0c\u4f46\u5c1a\u672a\u8b49\u660e\u5c0d\u4eba\u985e\u6709\u81f4\u764c\u98a8\u96aa\uff0c\u300c\u76ee\u524dmetformin\u6240\u5e36\u4f86\u7684\u6548\u76ca\u9060\u5927\u65bc\u5176\u53ef\u80fd\u5b58\u5728NDMA\u4e4b\u98a8\u96aa\uff0c\u6c11\u773e\u5207\u52ff\u81ea\u884c\u4efb\u610f\u505c\u85e5\u3002\u300d\n<\/p>\n

\u53e6\u5916\uff0c\u6839\u64da\u7f8e\u570b\u7cd6\u5c3f\u75c5\u5354\u6703\u6240\u516c\u5e03\u7684\u300c\u7cd6\u5c3f\u75c5\u91ab\u7642\u7167\u8b77\u6307\u5f15\uff08Standards of Medical care in diabetes, 2019\uff09\u300d\u53ca\u4e2d\u83ef\u6c11\u570b\u7cd6\u5c3f\u75c5\u5b78\u6703\u4e4b\u7cd6\u5c3f\u75c5\u81e8\u5e8a\u7167\u8b77\u6307\u5f15\uff0cmetformin\u70ba\u7b2c\u4e8c\u578b\u7cd6\u5c3f\u75c5\u4e4b\u7b2c\u4e00\u7dda\u7528\u85e5\uff0c\u5df2\u4f7f\u7528metformin\u4e4b\u75c5\u4eba\uff0c\u9664\u6709\u4e0d\u80fd\u4f7f\u7528metformin\u4e4b\u7981\u5fcc\u75c7\u5916\uff0c\u5747\u61c9\u6301\u7e8c\u4f7f\u7528\u3002<\/p>\n<\/p>\n

\u9ec3\u5efa\u5be7\u8868\u793a\uff0c\u82e5\u662f\u64c5\u81ea\u505c\u85e5\uff0c\u53ef\u80fd\u5c0e\u81f4\u8840\u7cd6\u63a7\u5236\u4e0d\u4f73\uff0c\u9032\u800c\u7522\u751f\u7cd6\u5c3f\u75c5\u5404\u9805\u6025\u6027\u6216\u6162\u6027\u4f75\u767c\u75c7\uff0c\u5982\u795e\u7d93\u75c5\u8b8a\u3001\u773c\u775b\u75c5\u8b8a\u3001\u814e\u81df\u75c5\u8b8a\uff0c\u751a\u81f3\u660f\u8ff7\u53ca\u6b7b\u4ea1\u7b49\u98a8\u96aa\u3002\n<\/p>\n<\/p>\n

\n

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\u53f0\u7063\u6c11\u773e\u8a72\u64d4\u5fc3\uff1f\u98df\u85e5\u7f72\uff1a44\u9805\u5177\u98a8\u96aa\u85e5\u54c1\u9001\u6aa2
\n<\/span><\/p>\n<\/p>\n

\n

\u98df\u85e5\u7f72\u56de\u61c9\u5df2\u65bc\u4e0a\u500b\u670813\u65e5\u51fd\u8acb\u85e5\u54c1\u76f8\u95dc\u516c\u5b78\u5354\u6703\uff0c\u8f49\u77e5\u85e5\u54c1\u88fd\u9020\u6216\u8f38\u5165\u696d\u8005\uff0c\u61c9\u4e3b\u52d5\u8a55\u4f30\u53ca\u6aa2\u6e2c\u85e5\u54c1\u88fd\u7a0b\u6240\u53ef\u80fd\u7522\u751f\u4e9e\u785d\u80fa\u985e\u4e0d\u7d14\u7269\u98a8\u96aa\u5916\uff0c\u4e14\u5df2\u91dd\u5c0d\u98a8\u96aa\u7a0b\u5ea6\u8f03\u9ad8\u7684\u6210\u5206\uff0c\u8981\u6c42\u696d\u8005\u61c9\u9010\u6279\u6aa2\u9a57\u539f\u6599\u85e5\uff0c\u7d93\u6aa2\u9a57\u5408\u683c\u8005\u624d\u80fd\u8f38\u5165\u6216\u4f9b\u88fd\u5291\u4f7f\u7528\u3002\n<\/p>\n<\/p>\n

\u53e6\u5916\uff0c\u7d93\u98df\u85e5\u7f72\u8490\u96c6\u570b\u969b\u6587\u737b\uff0c\u4e26\u8acb\u5c08\u5bb6\u5354\u52a9\u8a55\u4f30\u5f8c\uff0c\u5df2\u7be9\u907844\u9805\u53ef\u80fd\u5177NDMA\u98a8\u96aa\u4e4b\u85e5\u54c1\u6210\u5206\uff0c\u8acb\u696d\u8005\u512a\u5148\u4e88\u4ee5\u8a55\u4f30\u53ca\u6aa2\u9a57\u3002\u98df\u85e5\u7f72\u8868\u793a\u5c07\u6301\u7e8c\u57f7\u884c\u85e5\u54c1\u4e2d\u4e9e\u785d\u80fa\u985e\u4e0d\u7d14\u7269\u98a8\u96aa\u7ba1\u63a7\u63aa\u65bd\uff0c\u4ee5\u78ba\u4fdd\u85e5\u54c1\u54c1\u8cea\u5b89\u5168\uff0c\u82e5\u570b\u5167\u6709\u53d7\u5f71\u97ff\u7684\u85e5\u54c1\uff0c\u5c07\u5373\u6642\u516c\u5e03\u8cc7\u8a0a\uff0c\u4e26\u900f\u904e\u591a\u65b9\u7ba1\u9053\u63d0\u9192\u91ab\u7642\u4eba\u54e1\u53ca\u6c11\u773e\u6ce8\u610f\uff0c\u4ee5\u4fdd\u969c\u6c11\u773e\u7528\u85e5\u5b89\u5168\u3002<\/p>\n

\u9ec3\u5efa\u5be7\u4e5f\u5efa\u8b70\u6709\u670d\u7528metformin\u7684\u6c11\u773e\uff0c\u82e5\u4ecd\u6709\u7528\u85e5\u4e0a\u7684\u64d4\u5fc3\u6216\u4e0d\u78ba\u5b9a\uff0c\u53ef\u4ee5\u8ddf\u4e3b\u6cbb\u91ab\u5e2b\u591a\u8a0e\u8ad6\uff0c\u4ee5\u78ba\u4fdd\u7528\u85e5\u5b89\u5168\u3002<\/span><\/p>\n

\uff08\u672c\u6587\u8f49\u8f09\u81ea\u4fe1\u50b3\u5a92\uff09<\/p>\n

\n

\n

\u82e5\u6709\u670d\u85e5\u4efb\u4f55\u554f\u984c\uff0c\u6b61\u8fce\u81f3\u91ab\u5e2b\u5e73\u53f0\u767c\u554f\u2193<\/p>\n

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\u25fe\ufe0f \u4e86\u89e3\u5065\u5eb7\u6aa2\u67e5\uff1a https:\/\/med-net.com\/PrecisionMedicine <\/a> <\/span><\/p>\n

\u25fe\ufe0f \u7dda\u4e0a\u91ab\u5e2b\u8aee\u8a62\uff1a https:\/\/expert.med-net.com\/index <\/a> <\/span><\/p>\n

\u25fe\ufe0f \u77ed\u671f\u7167\u8b77\u670d\u52d9\uff1a https:\/\/pse.is\/47nzj5 <\/a> <\/span><\/p>\n

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