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\n

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\n

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\n

\u5927\u8166\u8377\u723e\u8499\u5931\u8abf\uff0c\u96e3\u602a\u4e0d\u597d\u7761<\/span><\/b><\/p>\n

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\n

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\n

GABA \u5c31\u662f\u03b3- \u80fa\u57fa\u4e01\u9178\uff0c\u4e00\u7a2e\u53ef\u4ee5\u8b93\u8166\u90e8\u4f11\u606f\u3001\u653e\u9b06\u7684\u795e\u7d93\u50b3\u5c0e\u7269\u8cea\uff0c\u7576GABA \u4e0d\u8db3\u6642\uff0c\u5c31\u6703\u89ba\u5f97\u8166\u5b50\u8f49\u500b\u4e0d\u505c\uff0c\u660e\u660e\u5f88\u7d2f\u537b\u7761\u4e0d\u8457\u3002<\/p>\n

\n

\u300c\u8178\u300d\u88ab\u5ffd\u7565\u7684\u77e5\u8b58<\/span>
\n<\/span><\/span><\/p>\n

\u8178\u9053\u83cc\u4e5f\u548c\u5931\u7720\u6709\u95dc
\n<\/span><\/p>\n

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\n

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\n

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\n

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\n

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\n<\/span><\/p>\n

\u25cf\u76ca\u751f\u83cc
\n<\/span><\/p>\n

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\u25cf\u76ca\u751f\u8cea
\n<\/span><\/p>\n

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\u25cf\u904b\u52d5
\n<\/span><\/p>\n

\u990a\u6210\u898f\u5f8b\u904b\u52d5\u7684\u7fd2\u6163\uff0c\u7d55\u5c0d\u662f\u5c0d\u6297\u6162\u6027\u58d3\u529b\u7684\u4e0d\u4e8c\u6cd5\u9580\u3002\u4e0d\u904e\u5927\u5bb6\u7d55\u5c0d\u60f3\u4e0d\u5230\uff0c\u904b\u52d5\u4e5f\u53ef\u4ee5\u8abf\u6574\u8178\u9053\u4e2d\u597d\u83cc\u8207\u58de\u83cc\u7684\u6bd4\u4f8b\uff0c\u964d\u4f4e\u9ad4\u5167\u767c\u708e\u72c0\u614b\uff0c\u9593\u63a5\u5f71\u97ff\u7761\u7720\u72c0\u614b\u3002\u71df\u990a\u5e2b\u5efa\u8b70\u5927\u5bb6\uff0c\u5728\u7761\u524d\u53ef\u4ee5\u9032\u884c\u4ee5\u653e\u9b06\u6216\u4f38\u5c55\u70ba\u4e3b\u7684\u4f4e\u5f37\u5ea6\u7c21\u6613\u904b\u52d5\uff0c\u642d\u914d\u547c\u5438\u8abf\u6574\uff0c\u8b93\u5fd9\u788c\u4e00\u6574\u5929\u7684\u8eab\u9ad4\u5728\u7761\u524d\u80fd\u5920\u56de\u6b78\u5e73\u975c\u3002\n<\/p>\n

\u25cf\u5176\u4ed6\u8207\u52a9\u7720\u6709\u95dc\u7684\u71df\u990a\u7d20
\n<\/span><\/p>\n

<\/p>\n

\u9032\u968e\u300c\u8178\u300d\u8b58<\/span><\/span><\/p>\n

\u25cf\u96a8\u65e5\u591c\u9031\u671f\u800c\u8b8a\u5316\u7684\u8178\u9053\u83cc
\n<\/span><\/p>\n

\u76ee\u524d\u767c\u73fe\u6703\u96a8\u8457\u65e5\u591c\u9031\u671f\u800c\u6709\u6578\u91cf\u8b8a\u5316\u7684\u8178\u9053\u83cc\u7a2e\u5305\u62ec\uff1aClostridiales\u3001Lactobacillales\u3001Bacteroidales \u8207Firmicutes \u7b49\u3002\n<\/p>\n

\u25cf\u8178\u9053\u83cc\u8207\u8840\u6e05\u7d20
\n<\/span><\/p>\n

\u4eba\u9ad4\u7684\u8840\u6e05\u7d20\u4e3b\u8981\u662f\u7531\u8178\u9053\u9ecf\u819c\u7684\u55dc\u927b\u6027\u7d30\u80de\uff08chromaffin cells\uff09\u5408\u6210\uff0c\u8178\u9053\u83cc\u53ef\u900f\u904e\u7522\u751f\u77ed\u93c8\u8102\u80aa\u9178\u6216\u6b21\u7d1a\u81bd\u9178\u7b49\u65b9\u5f0f\uff0c\u76f4\u63a5\u5f71\u97ff\u8840\u6e05\u7d20\u5408\u6210\u7684\u95dc\u9375\u9175\u7d20\uff0c\u4fc3\u9032\u55dc\u927b\u6027\u7d30\u80de\u4e2d\u8840\u6e05\u7d20\u7684\u542b\u91cf\uff1b\u7814\u7a76\u4e5f\u767c\u73fe\uff0c\u8178\u9053\u4e2d\u5e38\u898b\u7684Escherichia coli \u8207Enterococcus \u83cc\u7a2e\uff0c\u4e5f\u80fd\u81ea\u884c\u5408\u6210\u5c11\u91cf\u7684\u8840\u6e05\u7d20\uff0c\u9593\u63a5\u5f71\u97ff\u6211\u5011\u7684\u7761\u7720\u54c1\u8cea\u8207\u5fc3\u60c5\u3002\u96d6\u7136\u8840\u6e05\u7d20\u6703\u56e0\u70ba\u8840\u8166\u5c4f\u969c\u7684\u9650\u5236\uff0c\u7121\u6cd5\u76f4\u63a5\u4f5c\u7528\u65bc\u8166\u90e8\uff0c\u4f46\u8d8a\u4f86\u8d8a\u591a\u7814\u7a76\u8a8d\u70ba\uff0c\u8178\u9053\u83cc\u53ef\u5f71\u97ff\u8178\u9053\u8207\u8840\u6db2\u4e2d\u8272\u80fa\u9178\uff08\u8b93\u8840\u6e05\u7d20\u80fd\u9806\u5229\u5408\u6210\u7684\u91cd\u8981\u71df\u990a\u7d20\u4e4b\u4e00\uff09\u7684\u4ee3\u8b1d\uff0c\u8abf\u7bc0\u5927\u8166\u4e2d\u8272\u80fa\u9178\u6fc3\u5ea6\uff0c\u9032\u800c\u5f71\u97ff\u5927\u8166\u4e2d\u8840\u6e05\u7d20\u7684\u5408\u6210\u91cf\u3002\n<\/p>\n

\u25cf\u80fd\u7522\u751f\u8840\u6e05\u7d20\u7684\u8178\u9053\u83cc
\n<\/span><\/p>\n

\u76ee\u524d\u5df2\u77e5\u53ef\u7522\u751f\u8840\u6e05\u7d20\u7684\u8178\u9053\u83cc\u7a2e\uff0c\u6574\u7406\u5982\u4e0b\uff1a
\n<\/span><\/p>\n

Escherichia coli (K-12)\n<\/p>\n

Hafnia alvei (NCIMB, 11999)\n<\/p>\n

Klebsiella pneumoniae (NCIMB, 673)\n<\/p>\n

Lactobacillus plantarum (FI8595)\n<\/p>\n

Lactococcus lactis subsp. cremoris (MG 1363)\n<\/p>\n

Morganella morganii (NCIMB, 10466)\n<\/p>\n

Streptococcus thermophilus (NCFB2392)\n<\/p>\n

\u25cf\u98f2\u98df\u4e2d\u7684 GABA \u8207\u5927\u8166\u8840\u8166\u5c4f\u969c
\n<\/span><\/p>\n

\u5e02\u9762\u4e00\u4e9b\u4fdd\u5065\u98df\u54c1\u76f4\u63a5\u63d0\u4f9bGABA\uff0c\u6a19\u699c\u88dc\u5145\u53ef\u4ee5\u5e6b\u52a9\u5165\u7761\u3002\u96d6\u7136\u76ee\u524d\u4ecd\u7136\u7f3a\u4e4f\u76f4\u63a5\u6e2c\u91cfGABA \u901a\u904e\u5927\u8166\u8840\u8166\u5c4f\u969c\u7684\u4eba\u9ad4\u8a66\u9a57\uff0c\u4f46\u591a\u6578\u7684\u7814\u7a76\u4f9d\u820a\u8a8d\u70ba\uff0cGABA \u672c\u8eab\u662f\u7121\u6cd5\u901a\u904e\u5927\u8166\u8840\u8166\u5c4f\u969c\u7684\uff0c\u5c31\u7b97\u6709\uff0c\u4e5f\u662f\u6975\u5fae\u91cf\uff1b\u4e5f\u5c31\u662f\u8aaa\uff0c\u6211\u5011\u5403\u9032\u53bb\u7684GABA \u8981\u9001\u5230\u8166\u90e8\u6642\uff0c\u5e7e\u4e4e\u90fd\u6703\u88ab\u64cb\u5728\u5916\u9762\u3002\u79d1\u5b78\u5bb6\u5c0d\u65bcGABA \u662f\u5426\u53ef\u4ee5\u7a7f\u8d8a\u5927\u8166\u8840\u8166\u5c4f\u969c\u7684\u770b\u6cd5\u4e0d\u4e00\u81f4\uff0c\u53ef\u6b78\u56e0\u65bc\u4e0d\u540c\u7814\u7a76\u7684\u5be6\u9a57\u8a2d\u8a08\u5dee\u7570\uff1a\n<\/p>\n

(1) \u7d66\u4e88\u5f62\u5f0f\u4e0d\u540c\uff0c\u5982\u5e36\u7fa5\u57fa\u7684GABA \u76f8\u4f3c\u7269\u3001\u653e\u5c04\u6027\u6a19\u5b9a\u7b49\u4e0d\u540c\u5f62\u5f0f\u3002
\n<\/span><\/p>\n

(2) \u4ecb\u5165\u65b9\u5f0f\u4e0d\u540c\uff0c\u5305\u62ec\u53e3\u670d\u3001\u8179\u8154\u6216\u975c\u8108\u6ce8\u5c04\u3001\u8166\u90e8\u704c\u6d41\u7b49\u6a21\u5f0f\u3002
\n<\/span><\/p>\n

(3) \u5be6\u9a57\u52d5\u7269\u7a2e\u985e\u4e0d\u540c\uff0c\u5e38\u898b\u7684\u5305\u62ec\u5927\u9f20\u3001\u5c0f\u9f20\u3001\u5154\u5b50\u6216\u72d7\u3002
\n<\/span><\/p>\n

(4) \u81e8\u5e8a\u8a66\u9a57\u4eba\u6578\u591a\u5be1\uff0c\u6216\u7814\u7a76\u5718\u968a\u8207\u7814\u7a76\u8d0a\u52a9\u5ee0\u5546\u7684\u5229\u76ca\u885d\u7a81\u7b49\u56e0\u7d20\u3002<\/span><\/p>\n

\n

\u25cf\u8178\u9053\u83cc\u8207 GABA
\n<\/span><\/p>\n

\u5fae\u751f\u7269\u767c\u9175\u6cd5\u70ba\u76ee\u524d\u696d\u754c\u751f\u7522GABA \u7684\u5e38\u7528\u65b9\u5f0f\uff0c\u9ea9\u80fa\u9178\u7d93\u7531\u9175\u7d20\u8f49\u5316\u4f5c\u7528\u5f8c\uff0c\u5373\u53ef\u7522\u751fGABA\u3002Lactobacillus \u8207Bifidobacterium \u9019\u5169\u7a2e\u5e38\u898b\u7684\u76ca\u751f\u83cc\uff0c\u70ba\u76ee\u524d\u8a31\u591a\u7814\u7a76\u751f\u7522\u9ad8\u6fc3\u5ea6GABA \u7684\u4ee3\u8868\u83cc\u7a2e\u3002\u79d1\u5b78\u5bb6\u4e5f\u8a8d\u70ba\uff0c\u8178\u9053\u4e2d\u7684\u76ca\u751f\u83cc\u78ba\u5be6\u53ef\u4ee5\u5354\u52a9\u90e8\u5206GABA \u7684\u5408\u6210\uff0c\u900f\u904e\u526f\u4ea4\u611f\u795e\u7d93\u7cfb\u7d71\u4e2d\u7684\u8ff7\u8d70\u795e\u7d93\u5f71\u97ff\u6211\u5011\u7684\u5927\u8166\u3002\u5728\u8a31\u591a\u52d5\u7269\u5be6\u9a57\u767c\u73fe\uff0c\u76f8\u8f03\u65bc\u63a7\u5236\u7d44\uff0c\u98fc\u6599\u4e2d\u542b\u6709Lactobacillus rhamnosus \u7684\u5c0f\u9f20\uff0c\u5728\u9762\u5c0d\u5916\u5728\u58d3\u529b\u523a\u6fc0\u6642\uff0c\u58d3\u529b\u8377\u723e\u8499\u76ae\u8cea\u9187\u7684\u6fc3\u5ea6\u660e\u986f\u8f03\u4f4e\uff0c\u8f03\u4e0d\u5bb9\u6613\u51fa\u73fe\u6182\u9b31\u7684\u76f8\u95dc\u75c7\u72c0\uff0c\u4e26\u4e14\u5927\u8166\u88e1GABA \u53d7\u9ad4\u7684mRNA \u8868\u73fe\u91cf\u660e\u986f\u6539\u8b8a\u3002\u503c\u5f97\u6ce8\u610f\u7684\u662f\uff0c\u7576\u5207\u9664\u5be6\u9a57\u5c0f\u9f20\u7684\u8ff7\u8d70\u795e\u7d93\u5f8c\uff0c\u4e0a\u8ff0\u8207GABA \u964d\u4f4e\u58d3\u529b\u7684\u6548\u679c\u90fd\u6703\u88ab\u963b\u65b7\u3002\u9019\u4e9b\u6216\u8a31\u90fd\u53ef\u4ee5\u8aaa\u660eGABA \u96d6\u7136\u4e0d\u80fd\u901a\u904e\u5927\u8166\u8840\u8166\u5c4f\u969c\uff0c\u4f46\u53ef\u4ee5\u900f\u904e\u8ff7\u8d70\u795e\u7d93\u5f9e\u8178\u9053\u5f71\u97ff\u5927\u8166\uff0c\u6539\u8b8a\u8166\u4e2dGABA \u7684\u5408\u6210\u6578\u91cf\u3002<\/p>\n

\n

\u25cf\u80fd\u5408\u6210 GABA \u7684\u8178\u9053\u83cc
\n<\/span><\/p>\n

\u76ee\u524d\u5df2\u77e5\u53ef\u7522\u751fGABA \u7684Lactobacillus \u8207Bifidobacterium\uff0c\u6574\u7406\u5982\u4e0b\uff1a
\n<\/span><\/p>\n

\u672c\u6587\u5f15\u7528\u4f86\u6e90\uff1a\u3010\u8178\u9053\u83cc\u5c0d\u4e86\u8eab\u5fc3\u5c31\u5065\u5eb7\uff01\u71df\u990a\u5b78\u5c08\u5bb6\u7684\u8b77\u8178\u98f2\u98df\u5168\u6307\u5357\u3011\uff0c\u5433\u6620\u84c9\uff0e\u7fc1\u5fb7\u5fd7\uff0e\u674e\u82b7\u8587 \u5408\u8457\uff0c\u81c9\u8b5c\u51fa\u7248<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

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