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\n<\/span><\/p>\n

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\u8a72\u4e2d\u5fc3\u7684\u7d04\u7ff0\u2027\u79d1\u842c\uff08John Kirwan\uff09\u535a\u58eb\u8868\u793a\uff0c\u88ab\u65b0\u51a0\u75c5\u6bd2\u5f8c\u907a\u75c7\u6240\u56f0\u7684\u60a3\u8005\u6578\u4e26\u4e0d\u660e\u78ba\uff0c\u4f46\u63a8\u4f30\u7d04\u670915\uff05\uff5e80\uff05\u3002\u9664\u4e86\u5f37\u70c8\u7684\u75b2\u52de\u3001\u5473\u55c5\u89ba\u7570\u5e38\u3001\u767c\u71d2\u7b49\u554f\u984c\u5916\uff0c\u9084\u6709\u53ef\u80fd\u5c0e\u81f4\u7cd6\u5c3f\u75c5\uff0c\u5176\u4e2d\u751a\u81f3\u6709\u60a3\u8005\u75c7\u72c0\u65b0\u51a0\u75c5\u6bd2\u75c7\u72c0\u4e26\u4e0d\u660e\u986f\uff0c\u537b\u5728\u5eb7\u5fa9\u5f8c\u534a\u5e74\u88ab\u8a3a\u65b7\u51fa\u7cd6\u5c3f\u75c5\u3002<\/p>\n

\u540c\u5c6c\u6f58\u5be7\u9813\u751f\u7269\u91ab\u5b78\u7814\u7a76\u4e2d\u5fc3\u7684\u7814\u7a76\u54e1\u574e\u8482\u96c5\u2027\u96f7\u8c9d\u6d1b\uff08Candida Rebello\uff09\u535a\u58eb\u4e5f\u8868\u793a\uff0c\u65b0\u51a0\u75c5\u6bd2\u7684\u611f\u67d3\u53ef\u80fd\u5f15\u767c\u6182\u9b31\u75c7\u3001\u7cd6\u5c3f\u75c5\u7b49\u554f\u984c\uff0c\u6703\u8b93\u8840\u7cd6\u4e0a\u5347\uff0c\u4f7f\u7cd6\u5c3f\u75c5\u916e\u9178\u8840\u75c7\uff08Diabetic ketoacidosis, DKA\uff09\u7684\u5371\u96aa\u6027\u63d0\u9ad8\uff0c\u9019\u662f\u4e00\u7a2e\u5e38\u898b\u65bc1\u578b\u7cd6\u5c3f\u75c5\u60a3\u8005\u7684\u5371\u96aa\u72c0\u614b\u3002<\/p>\n

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\u916e\u9178\u8840\u75c7\u53c8\u7a31\u916e\u9178\u4e2d\u6bd2\uff0c\u6700\u56b4\u91cd\u7684\u60c5\u6cc1\u4e0b\u6709\u53ef\u80fd\u6703\u5371\u53ca\u6027\u547d\uff0c\u82e5\u51fa\u73fe\u809a\u5b50\u75db\u3001\u5641\u5fc3\uff0c\u547c\u5438\u6025\u4fc3\u7b49\u75c7\u72c0\uff0c\u6216\u662f\u660f\u7761\u3001\u610f\u8b58\u4e0d\u6e05\u7b49\u554f\u984c\uff0c\u52d9\u5fc5\u76e1\u65e9\u5c31\u91ab\u6cbb\u7642\u3002<\/p>\n

\u9069\u5ea6\u904b\u52d5\u53ef\u671b\u6210\u70ba\u65b0\u51a0\u75c5\u6bd2\u5f8c\u907a\u75c7\u89e3\u65b9\uff0c\u5efa\u8b70\u5148\u5f9e\u6bcf\u5929\u5065\u8d7030\u5206\u9418\u505a\u8d77<\/span><\/p>\n

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\u5148\u8a2d\u5b9a\u7c21\u55ae\u7684\u76ee\u6a19\uff0c\u4f8b\u5982\u4e00\u5929\u5408\u8a0830\u5206\u9418\u7684\u904b\u52d5\uff0c\u5982\u679c\u6bcf\u6b21\u9ad4\u529b\u53ea\u80fd\u649015\u5206\u9418\uff0c\u90a3\u9ebc\u5c31\u5206\u5169\u6b21\u9032\u884c\uff0c\u52a0\u8d77\u4f8630\u5206\u9418\u5c31\u597d\uff0c\u66f4\u91cd\u8981\u7684\u662f\u6301\u4e4b\u4ee5\u6046\u5730\u53bb\u505a\u3002\u7576\u4f60\u7fd2\u6163\u4e86\uff0c\u5c31\u80fd\u9010\u6f38\u589e\u52a0\u904b\u52d5\u91cf\uff0c\u6700\u7d42\u9054\u5230\u8a2d\u5b9a\u7684\u76ee\u6a19\u3002<\/p>\n

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\u904b\u52d5\u4e4b\u6240\u4ee5\u53ef\u671b\u6539\u5584\u5f8c\u907a\u75c7\uff0c\u53ef\u80fd\u548c\u611f\u67d3\u65b0\u51a0\u75c5\u6bd2\u6240\u5f15\u767c\u7684\u300c\u7d30\u80de\u6fc0\u7d20\u98a8\u66b4\uff08cytokine storm\uff09\u300d\u6709\u95dc\u3002\u7576\u4eba\u9ad4\u88ab\u65b0\u51a0\u75c5\u6bd2\u611f\u67d3\uff0c\u53ef\u80fd\u6703\u56e0\u70ba\u58d3\u529b\u3001\u767c\u708e\uff0c\u4ee5\u53ca\u8ca0\u8cac\u5206\u6ccc\u80f0\u5cf6\u7d20\u7684\u03b2\u7d30\u80de\u529f\u80fd\u7570\u5e38\u7b49\u56e0\u7d20\u5f15\u767c\u9ad8\u8840\u7cd6\u554f\u984c\u3002<\/p>\n

\u9ad8\u8840\u7cd6\u6703\u8b93\u80f0\u81df\u03b2\u7d30\u80de\u4e2d\u7684NLRP3\u767c\u708e\u9ad4\u88ab\u6d3b\u5316\uff0c\u9020\u6210\u767c\u71d2\u3001\u767c\u708e\u7b49\u3002\u7dca\u63a5\u8457\uff0c\u03b2\u7d30\u80de\u91cb\u653e\u51fa\u7684\u7d30\u80de\u56e0\u5b50\u300cIL-1\u03b2\u300d\u6703\u589e\u52a0\uff0c\u9019\u662f\u4e00\u7a2e\u548c\u75c5\u6bd2\u611f\u67d3\u6240\u9020\u6210\u7684\u767c\u708e\u53cd\u61c9\u6709\u95dc\u7684\u7269\u8cea\u3002<\/p>\n

\u82e5\u662fIL-1\u03b2\u589e\u52a0\uff0c\u53ef\u80fd\u6703\u963b\u7919\u80f0\u5cf6\u7d20\u5206\u6ccc\u3001\u8b93\u03b2\u7d30\u80de\u7684\u529f\u80fd\u53d7\u5230\u5f71\u97ff\uff0c\u4e5f\u53ef\u80fd\u5c0e\u81f4\u7d30\u80de\u51cb\u4ea1\uff0c\u8b93\u8840\u7cd6\u53c8\u518d\u5ea6\u4e0a\u5347\uff0c\u9677\u5165\u60e1\u6027\u5faa\u74b0\u4e4b\u4e2d\u3002<\/p>\n

\u800c\u904b\u52d5\u4e0d\u53ea\u80fd\u5920\u964d\u4f4e\u8840\u7cd6\uff0c\u9084\u80fd\u4fc3\u9032\u9ad4\u5167\u5177\u5099\u6297\u767c\u708e\u6548\u679c\u7684\u7269\u8cea\u91cb\u51fa\uff0c\u9084\u80fd\u6539\u5584\u80f0\u5cf6\u7d20\u963b\u6297\u7b49\u3002\u7c21\u800c\u8a00\u4e4b\uff0c\u904b\u52d5\u53ef\u80fd\u8b93\u767c\u708e\u5f15\u767c\u7684\u9023\u9396\u53cd\u61c9\u88ab\u65ac\u65b7\uff0c\u4f7f\u65b0\u51a0\u75c5\u6bd2\u5f8c\u907a\u75c7\u53ef\u80fd\u66f4\u5bb9\u6613\u75ca\u7652\u3002<\/p>\n

\u904b\u52d5\u4e0d\u53ea\u6539\u5584\u5f8c\u907a\u75c7\uff0c\u9084\u80fd\u5e6b\u52a9\u5c1a\u672a\u7f79\u60a3\u65b0\u51a0\u75c5\u6bd2\u8005\u964d\u4f4e\u4f4f\u9662\u98a8\u96aa<\/span><\/p>\n

\u904b\u52d5\u7684\u597d\u8655\u7576\u7136\u4e0d\u53ea\u662f\u80fd\u6539\u5584\u5f8c\u907a\u75c7\uff0c\u5373\u4f7f\u662f\u5c0d\u672a\u67d3\u75ab\u7684\u4eba\u4f86\u8aaa\uff0c\u76e1\u65e9\u57f9\u990a\u904b\u52d5\u7fd2\u6163\u90fd\u662f\u975e\u5e38\u6709\u5fc5\u8981\u7684\u3002\u904e\u53bb\u4e00\u9805\u7814\u7a76\u7d71\u8a08\u4e8648,440\u4eba\u7684\u8cc7\u6599\uff0c\u4e26\u5206\u6790\u65b0\u51a0\u75ab\u60c5\u958b\u59cb\u5927\u6d41\u884c2\u5e74\u524d\u4ed6\u5011\u7684\u904b\u52d5\u7fd2\u6163\uff0c\u53ca\u5176\u611f\u67d3\u65b0\u51a0\u75c5\u6bd2\u5f8c\u4f4f\u9662\u3001\u4f4f\u9032\u52a0\u8b77\u75c5\u623f\u7684\u98a8\u96aa\u3002<\/p>\n

\u7d50\u679c\u767c\u73fe\u6c92\u6709\u904b\u52d5\u7fd2\u6163\u7684\u65cf\u7fa4\uff0c\u6bd4\u8d77\u6709\u904b\u52d5\u7fd2\u6163\u7684\u65cf\u7fa4\uff0c\u4f4f\u9662\u7684\u98a8\u96aa\u70ba2.26\u500d\uff0c\u4f4f\u9032\u52a0\u8b77\u75c5\u623f\u7684\u98a8\u96aa\u70ba1.73\u500d\u3002\u4e5f\u5c31\u662f\u8aaa\u6709\u904b\u52d5\u7fd2\u6163\u7684\u4eba\u5373\u4f7f\u611f\u67d3\u4e86\u65b0\u51a0\u75c5\u6bd2\uff0c\u4f46\u75c5\u60c5\u56b4\u91cd\u5230\u5fc5\u9808\u4f4f\u9662\u3001\u4f4f\u9032\u52a0\u8b77\u75c5\u623f\u7684\u98a8\u96aa\u90fd\u6703\u6bd4\u8f03\u4f4e\u3002<\/p>\n

\u4f46\u4e5f\u63d0\u9192\u60a8\uff0c\u6bcf\u500b\u4eba\u8eab\u9ad4\u72c0\u6cc1\u4e0d\u540c\uff0c\u904b\u52d5\u53ef\u80fd\u5e36\u4f86\u7684\u98a8\u96aa\u4e5f\u4e0d\u76e1\u76f8\u540c\uff0c\u904b\u52d5\u662f\u5426\u5c0d\u75c5\u60c5\u6709\u76ca\u3001\u5982\u4f55\u62ff\u634f\u904b\u52d5\u5f37\u5ea6\uff0c\u4ecd\u61c9\u8996\u5c08\u696d\u91ab\u5e2b\u5224\u65b7\u800c\u6709\u6240\u8abf\u6574\u3002<\/p>\n

\u64b0\u6587\u8005\uff1a\u91ab\u806f\u7db2\u7de8\u8f2f\u7fa4<\/p>\n

\u5be9\u95b1\u8005\uff1a\u7f85\u6587\u573b \u91ab\u5e2b<\/p>\n

\u4f60\u9084\u6703\u60f3\u77e5\u9053\u25bc<\/span><\/p>\n

\u25cf\u3010\u547c\u5438\u56f0\u96e3\u3011\u6e2c\u4e00\u6e2c\uff01
\n<\/span><\/p>\n

>> https:\/\/medi.pse.is\/4ahzb2<\/a><\/p>\n

\u25cf \u70ba\u60a8\u63a8\u85a6\u5c08\u5c6c\u3010\u5065\u6aa2\u65b9\u6848\u3011\uff01<\/span><\/p>\n

>> https:\/\/medi.pse.is\/4a76nr<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"

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